Anthrogen launches Odyssey, a family of protein language models scaled to 102 billion parameters. It is the largest and most powerful biological model ever created.
- It allows us to rationally design and optimize proteins toward multi-objective goals--for example, “binds the target,” and “low side effects,” and “manufacturable at scale.”
- Proteins life's workhorses; being able to rationally design new molecular machines with the same precision we can design macro machines/robots is Anthrogen's north star. Odyssey is an important first step in that direction.
- We introduce Consensus, a more scaling-robust replacement for self-attention that cuts the cost of generating longer, more intricate proteins and trains stably.
- We train with discrete diffusion, a learning objective that mirrors evolution: forward steps inject mutations; the reverse process learns to select sequences and structures that work together.
- We demonstrate Odyssey's ability to learn very data-efficiently. With proteins, data is scarce--we achieve better performance than competing models with ~10x less data.
Articles
- (2025-10-18) Anthrogen introduces Odyssey, the world's largest and most powerful protein language model
- (2025-10-15) Odyssey: reconstructing evolution through emergent consensus in the global proteome